Technical R&D – Analytical Project Lead (7179)

Technical R&D – Analytical Project Lead

Join a pioneering force in Drug Discovery and Development and a frontrunner in Personalised Healthcare. As the world's largest R&D spender in the pharmaceutical and diagnostics domain, this client is highly recognized internationally for its work across a vast number of therapeutic areas. They are a leader in both in vitro diagnostics and the manufacturing and selling of innovative drugs, supporting research, early development, and clinical trials through technical innovation and collaboration.

This role is based in Basel, Switzerland, with a contract duration of one year (with a very high chance of extension) and a starting date of 01.03.2027. Within the Synthetic Molecules Technical Development (PTDC) team, you will specialize in drug substance, drug product, and analytical sciences. The position focuses on analytical development for synthetic molecules, employing cutting-edge techniques such as high-performance liquid chromatography, gas/ion chromatography, and mass spectrometry to develop efficient and robust analytical methods. The goal is to ensure the release of clinical trial products and their eventual commercial supply through a strong control strategy.

Main Responsibilities

• Serve as the Analytical SME/analytical project lead (APL), driving the development of state-of-the-art analytical control packages for synthetic molecules, including direct materials, IPCs, intermediates, and crude APIs.
• Actively contribute to portfolio delivery by ensuring efficient and effective process development analytics, including the adoption of modern techniques like modeling and simulation.
• Coach technicians and junior scientists on project work and serve as a central point of contact for project-related information.
• Supervise internal laboratory activities and/or testing activities at CLOs/CDMOs.
• Collaborate cross-functionally with key partners in research and early development, Regulatory, and Quality to ensure seamless project execution and alignment.
• Author, review, and approve critical documents and regulatory dossiers (e.g., QIMPD, NDA) while ensuring compliance with quality standards and data integrity.
• Act as a Chemistry Project Lead (CPL), leading external testing activities at CDMOs or CLOs.

Qualifications and Experience

• Relevant working/residency permit or Swiss/EU-Citizenship required.
• A Master's or Ph.D. in chemistry, pharmacy, or a related field.
• Minimum of 5 years of professional experience within the analytical development of synthetic peptides.
• Robust foundation in liquid chromatography (HPLC and UHPLC) with proficiency in various detection methods, including UV, Mass Spectrometry (MS), fluorescence, and charged aerosol detection.
• Solid understanding of analytical chemistry, particularly chromatographic techniques (HPLC, GC), titrations, and various physicochemical methods.
• Excellent collaboration, technical supervision, and project management skills, with a structured and rigorous approach.
• Digital acumen to support digital transformation initiatives; familiarity with statistical analysis of analytical data is also advantageous.
• Fluency in English is mandatory, German would be an advantage.