Research Scientist (in vivo) (7173)

Advance Next-Generation Radioligand Therapies in Oncology

Join a leading global pharmaceutical organization headquartered in Basel, Switzerland, as it undergoes a significant transformation in culture and external perception. This organization focuses on novel therapies in Oncology and Ophthalmology while developing a world-leading pipeline in Neuroscience and Dermatology, boasting one of the strongest portfolios of Phase II/III studies globally. As a specialized search and recruitment partner for the Life Sciences industry since 1997, we are connecting talented professionals with meaningful opportunities to support this client in engaging, retaining, and developing the right talent.

Role Overview

Leverage your expertise in in vivo oncology to help advance the next generation of radioligand therapies (RLT). By developing and characterizing oncology models, evaluating novel treatments, and generating critical insights, your work will directly support the client’s world-leading Oncology portfolio. This position is available on a two-year contract basis in Basel.

Key Responsibilities

• Develop and characterize novel in vivo oncology models to support preclinical radioligand therapy research
• Conduct efficacy studies evaluating novel radioligand therapies across various oncology programs
• Perform biodistribution studies and metabolite analyses to inform pharmacology decisions
• Conduct small-animal positron emission tomography (PET), single-photon emission computed tomography (SPECT), and computed tomography (CT) imaging studies
• Support in vitro and ex vivo activities, including cell culture, flow cytometry, immunohistochemistry, immunofluorescence, autoradiography, polymerase chain reaction, and Western blotting

Required Profile

• Relevant working/residency permit or Swiss/EU-Citizenship required
• Practical in vivo experience gained within an academic or industry biomedical research laboratory
• Bachelor's or Master's degree in Cell Biology, Medical Physics, Bioengineering, Biotechnology, Pharmacology, or a related field
• Hands-on experience with rodent handling and in vivo oncology models, including dosing, sampling, and animal welfare requirements
• Training and practical experience working safely with open radioactive sources
• Experience with positron emission tomography, single-photon emission computed tomography, or computed tomography imaging in rodents and subsequent image analysis
• Experience with cellular and molecular biology methods
• Experience with immunohistochemistry, tissue processing, and sectioning
• Advanced written and spoken English, with the ability to communicate scientific findings effectively